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New method to grow blood vessels of Heart

 
American scientists have used controlled doses of a human protein to get hearts to grow their own arteries. Normally the bypass surgery involves stopping the heart, for which some patients may be too ill. A team of Harvard scientists have found a solution to this.

Michael Simons and colleagues report in the latest issue of the journal Ciculation that they implanted tiny timed-release capsules in to the heart muscles of patients waiting for bypass surgery. The capsules contained a hormone called basic fibroblast growth factor (bfGF). The hormone was delivered to the patient's heart over a four to six week period.
Baby hearts grow new blood vessels as they mature, but the adult heart donot grow new vessels.This test was to see if the growth factor could triger growth of new blood vessels through which blood could flow.

The patients getting 100 millinonths of a gram showed clear and significant improvement in blood flow, and they suffered no angina or chest pain. Those who got the lower dose got no worse. Those who were given only the placebo actually showed a worsening in blood flow during stress tests and they suffered chest pain.

This study involved only 24 patients. After treatment blood flow was measured by two sophisticated tests, involving magnetic and nuclear stress testing.

A bigger trail has begun involving 120 patients.

Could this be a beginning of a new method of treating Ischemic Heart Disease !!

 
Cardiac Care
 
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