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An Enzyme may be key to Alzheimer's disease

Aging brains of apparently healthy people contain scattered amyloid plaques, whereas the brain of Alzheimer's Disease  patients are littered with them.  Scientists at Johns Hopkins have shown that a specific enzyme in the brain is essential for nerve cells to form the amyloid plaques which is a hallmark of Alzheimer'sdisease. This enzyme is beta-secretase. Blocking this enzyme can be a way out to treat this disease. 

gamma secretase

The research is published in the March edition of the journal Nature Neuroscience. It is funded by grants from the National Institute on Aging, Bristol-Myers Squibb Foundation and the Adler Foundation.

Physicians might ultimately give AD patients a "cocktail" of various enzyme-blockers or blockers along with vaccines.

 

 

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