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Insulin Discovery

 

Fredrick Banting and John Macleod were awarded the Nobel Prize for their discovery of Insulin. It was the first time that a Nobel Prize was awarded so soon after a discovery in 1923.

Banting, a young orthopaedic surgeon began working as a demonstrator in physiology in 1920 at the University of Eastern Ontario in Canada. Here in the laboratory of Mecleod and with the help of a medical student named C.H. Best, he conducted research into diabetes. They discovered that in diabetes the pancreas is unable to secrete enough of a hormone called Insulin which regulated the blood sugar level. They extracted the hormone in 1921 from the cells in the pancreas called the Islets of Langerhans. A young biochemist, J.B. Collip helped Banting and Best secure a regular supply of pig's pancreas glands from a local abattoir.  After a series of trails on dogs, injection of insulin was given to human patients with astounding success. 

In a wonderful show of large heartedness, both Banting and Macleod insisted on sharing the Prize with their colleagues Best and Collip.   

  

Nobel Prize for Medicine ' 99
List of Nobel Prize winners for Medicine

 

 

 
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