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This
disease, Alzheimer's disease was first described by a
German physician Alois Alzheimer 90 years ago. He first
demonstrated the typical microscopic changes in the
autopsy of a woman in her 50s who had suffered what
seemed to be a mental illness. Through microscope he saw
brain cells filled with twisted strands of fiber,
surrounded by dense deposits - these features are the
hallmarks of Alzheimer's disease. In this disorder gradual
decline of brain function leads inevitably to death,
anywhere from 3 to 20 years after the disease is
diagnosed.
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Child
Nutrition and Alzheimer's disease
Poorly nourished children appear to be at
increased risk of Alzheimer's disease as compared to well
nourished children. Those shorter than 5 feet have more
chance of developing symptoms of cognitive impairment. |
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New
Alzheimer's Gene Located.
A new study has located a Gene at a new place on
chromosome 12. The study has shown increased risk of late
onset Alzheimer's with this gene. A study conducted at
university of Toronto showed that APOE gene located on
chromosome 19, the one most commonly associated with late
onset Alzheimer's, accounted for much, but not all, the
risk in those with this disease. They also found that the
gene on chromosome 12 seems to play a role in the
Alzheimer's risk.
However, researchers at Washington University School of
Medicine in St Louis are unable to confirm this finding. |
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Should
Alzheimer's Drive ?
Auto accidents are often a early warning sign of
Alzheimer's disease. This has been shown by a
Scandinavian study. Driving demands rapid learning and
processing of new information and split second
decision-making based on newly learned material. This
depends on congnitive functions that are first to go in
many people with Alzheimer's disease. |
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Lithium
to Benefit Alzheimer's
Lithum has been used for treatment of Manic
depression. New research shows it may also help those
with Alzheimer's disease. It is found that abnormal
glutamate receptors play a role in manic depression.
Since glutamate receptors are implicated in the brain
cell death in Alzheimer's disease along with Huntington's
and Parkinson's disease. It raises the possibility of
lithium being useful in the treatment of these
neurodegenerative disorders. |
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Homocystine
linked to Alzheimer's
Researchers found high levels of Homocystine and
lower levels of nutrients that reduce homocystine levels
- folic acid and vitamin B12 in people diagnosed with
Alzheimer's disease.
High levels of homocystine has been repeatedly linked
with cardiovascular diseases. Also, cardiovascular
disease has been established as a major risk factor for
Alzheimer's disease. |
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Women
at Greater Risk of Alzheimer's
Women are about fifty percent more prone to
develop Alzheimer's as compared to men. Why women are at
increased risk is not known. Post menopausal hormonal
replacement can help women prevent this disease. |
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Large
family - increased risk of Alzheimer's disease.
Researchers at the University of
Washington in Seattle, Wash., found the risk for
Alzheimer's increases 8 percent with each additional
sibling. And people with five or more siblings have a 39
percent greater risk than those who grow up in smaller
families, according to the new study published in the
Jan. 25 Neurology, the journal of the American Academy of
Neurology. Researchers also found people who grow up in
urban areas are more likely to get Alzheimer's while risk
is lower among families who come from suburban or rural
areas.
So,
why is family size linked to Alzheimer's? "Families
with five or more children were more likely to be from
the lower socioeconomic levels and, therefore, more
likely to have poor growth rates," says lead
researcher Victoria Moceri. "A poor quality
childhood environment could prevent the brain from
reaching a complete level of maturation. The effects of
impaired development could produce a brain that is
normal, but functions less efficiently." |

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An adult's
diet has a direct impact on the risks of
developing Alzheimer's disease at an advanced
age, a recent study suggests. Eating foods
high in fat increases the risk of developing
Alzheimer's, while sticking to a diet high in
vegetables will diminish the chance of developing
the degenerative memory illness.
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| British biotech firm ReGen
Therapeutics Plc reported progress on development
of Colostrinin,
its potential treatment for Alzheimer's disease. The
company said three centers in Poland had begun
late-stage clinical trials and that all had
received favorable responses from their local
bio-ethics committees
Scientists from the Cambridge Addenbrooke
Hospital have developed a test that can detect the early
stages of Alzheimer disease in 10 minutes. Called the CANTAB
Paired Associated Learning Test, it can distinguish Alzheimer
sufferers from patients with depression and people without any
neuropsychiatric disorder, and is 98 per cent accurate.
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