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Dementia - Drug Therapy

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Dementia is a complex disorder which causes impairment in all areas of mental fuctions -
Memory and intellectual impairment ( cognitive )
Anxiety and depression ( mood )
Paranoia and Hallucination ( perception )
Agression or withdrawal.

Various neurotransmitters are said to be involved in the causation of Dementia -
Acetylcholine
Dopamine
Serotonin

Drugs for Congnitive and functional impairments in Dementia

These drugs increase the availability of Acetylcholine.
Tacrine
Rivastigmine
Donepezil
Newer drugs in future - Venlacrine,Galanthamine,Hyperazine.

Brain blood flow inhancers

These drugs increase blood perfusion and redistribute blood in the deficient areas.
Cyclandelate
Hydergine

Miscellaneous Drugs

Piracetam - a metabolic enhancing agent of the brain.
Selegiline- a MAOinhibitor, which is used in Parkinson's disease is also useful in Alzheimer's disease.
Aspirin and Other Anti inflammatory agents (NSAIDS) have also been shown to slow down the process of dementia.
Oestrogen replacement therapy may be helpful in postmenopausal women with dementia.
Ginkgo biloba
Brahmi
Ashwagandha

Researchers found that taking vitamins C and E might help protect the aging
mind from decline in cognitive function, and some kinds of dementia.

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