In the management of Malaria the important and critical aspect is the diagnosis and treatment of falciparum malaria as soon as possible as deterioration of the patient's condition can be rapid and sudden.
Besides drug treatment management of serious sign and symptoms are also very important.

Drug treatment of Malaria
Chloroquine: 600 mg immediately, 300 mg after 6 hrs., 300 mg on day 2, 300 mg on day 3 -- for all four types of malaria.

Artemether: For Chloroquine resistant falciparum malaria.
day 1 - 80 mg IM twice.
Next 4 days 80 mg Once daily.

Quinine: For Chloroquine resistant falciparum malaria.
Slow infusion over 4 hrs. Initial loading dose 20 mg /kg followed every 8 hrs. with 10mg / kg. for 10 days.

Mefloquine: For Chloroquine resistant falciparum malaria.
750 mg immediately. 500 mg 8 hrs. later.

Primaquine: given after a course of chloroquine for the elimination of P. vivax and P. ovale from the body.

Other drugs: Pyrimethamine/sulfadoxine combination. Doxycycline.

Caution :
Quinine or Chloroquine not to be given as IV bolus.
Dexamethasone IV , Manitol, Heparine to be avoided in Cerebral Malaria

Prophylactic medication for Malaria.

In endemic areas regular intake of chloroquine 2 tabs. for adults or Pyrimethamine/sulfadoxine 1 tab. for adults weekly may be use to prevent malaria.