| Class
of Drug |
Safety
|
Recommendation |
| Methyldopa |
Safe |
Treatment of Choice |
| Calcium Channel Blockers- Nifedipine |
Limited experience at present. |
Second line treatment |
| Betablockers - Propranolol,
Atenolol |
Limited experience in first
trimester. In Late Pregnancy can cause neonatal
hypoglycemia and bradycardia. |
Avoid in first trimester if
possible. |
| Diuretics - thiazides |
Theoretical risk of compromising
uteroplacental blood flow. |
Avoid |
| ACE Inhibitors - Captopril,
Enalapril |
Serious problems in the
foetus may occur such as oligohydramnious and
renal dysfuction after exposure in second and
third trimenster. |
Contraindicated |
| Angiotensin receptor antagonists - Losartan |
As for ACE inhibitors |
Contraindicated |
| |
