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The effects of 10 percent lemon juice on HIV in culture is that it kills the virus very quickly.
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Concentration of 20 percent lemon juice in a fresh human ejaculate irreversibly immobilizes 100 percent of spermatozoa in less than 30 seconds.
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It would be necessary to use only about 1ml of lemon juice in the vagina to inactivate HIV and sperm.
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Neat lemon juice applied to the vagina, or the penis and foreskin is not in any way painful to the user if no lesions are present.
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Lemon juice might also be very useful for post-coital washing of the penis, particularly the foreskin, to protect men from HIV infection. If lemons are in short supply, lime juice would be a good alternative.